AID in reprogramming: Quick and efficient
نویسندگان
چکیده
منابع مشابه
AID in reprogramming: quick and efficient: identification of a key enzyme called AID, and its activity in DNA demethylation, may help to overcome a pivotal epigenetic barrier in reprogramming somatic cells toward pluripotency.
Current methods of reprogramming differentiated cells into induced pluripotent stem cells remain slow and inefficient. In a recent report published online in Nature, Bhutani et al.1 developed a cell fusion strategy, achieving quick and efficient reprogramming toward pluripotency. Using this assay, they identified an immune system protein called activation-induced cytidine deaminase, or AID, whi...
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ژورنال
عنوان ژورنال: BioEssays
سال: 2010
ISSN: 0265-9247
DOI: 10.1002/bies.201000014